Secondary use of clinical data: the Vanderbilt approach

J Biomed Inform. 2014 Dec;52:28-35. doi: 10.1016/j.jbi.2014.02.003. Epub 2014 Feb 14.


The last decade has seen an exponential growth in the quantity of clinical data collected nationwide, triggering an increase in opportunities to reuse the data for biomedical research. The Vanderbilt research data warehouse framework consists of identified and de-identified clinical data repositories, fee-for-service custom services, and tools built atop the data layer to assist researchers across the enterprise. Providing resources dedicated to research initiatives benefits not only the research community, but also clinicians, patients and institutional leadership. This work provides a summary of our approach in the secondary use of clinical data for research domain, including a description of key components and a list of lessons learned, designed to assist others assembling similar services and infrastructure.

Keywords: Biomedical informatics; Research data warehouse; Research enterprise; Secondary use of clinical data.

MeSH terms

  • Biomedical Research / methods*
  • Database Management Systems*
  • Electronic Health Records
  • Humans
  • Medical Informatics / methods*