Colocalization of substance P and gamma-aminobutyric acid in amacrine cells of the cat retina

Brain Res. 1988 Apr 26;447(1):164-8. doi: 10.1016/0006-8993(88)90979-1.


Substance P and gamma-aminobutyric acid (GABA) were colocalized by immunocytochemistry in two subpopulations of amacrine cells in the cat retina. All of the cells which stained for substance P also showed GABA reactivity. However, there were many GABA-immunoreactive cells which did not stain for substance P. The presence of neuropeptides provides a basis for additional neurochemical characterization of the multiple populations of GABA immunoreactive cells.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antibodies, Monoclonal
  • Cats
  • Fluorescent Antibody Technique
  • Retina / cytology*
  • Substance P / analysis*
  • gamma-Aminobutyric Acid / analysis*


  • Antibodies, Monoclonal
  • Substance P
  • gamma-Aminobutyric Acid