Porcine dermal matrix in the treatment of dehiscence-type defects--an experimental split-mouth animal trial

Clin Oral Implants Res. 2015 Jul;26(7):799-805. doi: 10.1111/clr.12355. Epub 2014 Feb 19.


Objectives: To describe histometrical outcomes (tissue thickness, tissue height) of a porcine dermal matrix (PDX) and subepithelial connective tissue (CTG) in the treatment of dehiscence-type defects.

Material and methods: In five beagle dogs buccal dehiscence defects were created on both upper canines. The defects were covered in a split-mouth design either with a porcine dermal matrix or subepithelial connective tissue. After 4 months histometrical outcomes were evaluated using a nonparametric Brunner-Langer model.

Results: Neither in the test nor in the control specimen signs of inflammation or foreign body reaction was detected. Histometrically, no significant difference was found for tissue thickness and height between both treatment groups.

Conclusions: Porcine dermal matrix can be used for grafting of dehiscence-type defects. Augmentation of tissue thickness seems to be comparable to subepithelial connective tissue.

Keywords: dehiscence defect; porcine dermal matrix; root coverage.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acellular Dermis*
  • Animals
  • Biopsy
  • Connective Tissue / transplantation*
  • Dogs
  • Gingival Recession / surgery*
  • Gingivoplasty / methods*
  • Random Allocation
  • Surgical Flaps
  • Suture Techniques
  • Swine