Inducible nitric oxide synthase is crucial for plasma cell survival

Modesta N Njau; Joshy Jacob

doi:10.1038/ni.2831

Inducible nitric oxide synthase is crucial for plasma cell survival

Nat Immunol. 2014 Mar;15(3):219-21. doi: 10.1038/ni.2831.

Authors

Modesta N Njau¹, Joshy Jacob¹

Affiliation

¹ Emory Vaccine Center, Department of Microbiology & Immunology and Yerkes National Primate Center, Emory University, Atlanta, Georgia, USA.

PMID: 24549066
PMCID: PMC4480223
DOI: 10.1038/ni.2831

Abstract

The viability of long-lived plasma cells is enhanced by the expression of inducible nitric oxide synthase, which relieves endoplasmic reticulum stress by triggering a response dependent on cGMP and protein kinase G.

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MeSH terms

Animals
Nitric Oxide Synthase Type II / immunology*
Plasma Cells / immunology*
Signal Transduction / immunology*

Substances

Nitric Oxide Synthase Type II
Nos2 protein, mouse

Abstract

Publication types

MeSH terms

Substances

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