Iron inhibits the nonspecific tumoricidal activity of macrophages. A possible contributory mechanism for neoplasia in hemochromatosis

Ann N Y Acad Sci. 1988;526:301-9. doi: 10.1111/j.1749-6632.1988.tb55514.x.
No abstract available

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Apoferritins / pharmacology
  • Cytotoxicity Tests, Immunologic
  • Depression, Chemical
  • Hemochromatosis / chemically induced
  • Hemochromatosis / physiopathology
  • Interferons / biosynthesis
  • Iron / administration & dosage
  • Iron / pharmacology*
  • Iron / toxicity
  • Liposomes
  • Macrophage Activation / drug effects
  • Macrophages / drug effects*
  • Macrophages / physiology
  • Mice
  • Mice, Inbred BALB C
  • Mice, Inbred C3H
  • Mice, Inbred DBA
  • Phagocytosis / drug effects
  • Rats
  • Rats, Inbred Strains
  • Tumor Cells, Cultured

Substances

  • Liposomes
  • Interferons
  • Apoferritins
  • Iron