[Citalopram, escitalopram and prolonged QT: warning or alarm?]

Rev Psiquiatr Salud Ment. 2014 Jul-Sep;7(3):147-50. doi: 10.1016/j.rpsm.2013.12.005. Epub 2014 Feb 17.
[Article in Spanish]

Abstract

The alerts issued by regulatory agencies on the potential cardiac toxicity of citalopram and escitalopram have caused alarm among clinicians. A review of the data concerning this topic shows that the alarm should be limited to patients with a history of syncope or poisoning. As a precautionary measure, an electrocardiogram should be performed on elderly patients.

Keywords: Alerta; Cardiotoxicidad; Cardiotoxicity; Citalopram; Escitalopram; QT; Warning.

MeSH terms

  • Arrhythmias, Cardiac / chemically induced*
  • Brugada Syndrome
  • Cardiac Conduction System Disease
  • Citalopram / adverse effects*
  • Heart Conduction System / abnormalities*
  • Humans
  • Selective Serotonin Reuptake Inhibitors / adverse effects*

Substances

  • Citalopram
  • Selective Serotonin Reuptake Inhibitors