The battle in the gut

Immunity. 2014 Feb 20;40(2):173-5. doi: 10.1016/j.immuni.2014.01.007.

Abstract

Our molecular understanding of how pathogen-microbiota-immune system interactions influence disease outcomes is limited. In this issue of Immunity, Behnsen et al. (2014) report that the cytokine interleukin-22, which usually plays a protective role, promotes pathogen colonization by suppressing related commensal bacteria.

Publication types

  • Comment

MeSH terms

  • Animals
  • Host-Pathogen Interactions*
  • Interleukins / immunology*
  • Intestines / microbiology*
  • Salmonella Infections / immunology*
  • Salmonella Infections / microbiology*
  • Symbiosis / immunology*

Substances

  • Interleukins
  • interleukin-22