First report of plasmid-mediated fluoroquinolone efflux pump QepA in Escherichia coli clinical isolate ST68, in South America

Diagn Microbiol Infect Dis. 2014 May;79(1):70-2. doi: 10.1016/j.diagmicrobio.2014.01.007. Epub 2014 Jan 24.


This is the first report of the presence of qepA1 efflux pump gene in Escherichia coli clinical isolate from Argentina, which was associated to other plasmid-mediated quinolone resistance determinants, such as aac(6')-Ib-cr and qnrB10 and also quinolone resistance determining regions mutations.

Keywords: Fluoroquinolone resistance; PMQR; QRDR; qepA.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged, 80 and over
  • Argentina
  • DNA, Bacterial / analysis
  • DNA, Bacterial / genetics
  • Drug Resistance, Bacterial / genetics
  • Escherichia coli / drug effects
  • Escherichia coli / genetics*
  • Escherichia coli / metabolism
  • Escherichia coli Infections / microbiology*
  • Escherichia coli Proteins / genetics*
  • Female
  • Humans
  • Plasmids / genetics*


  • DNA, Bacterial
  • Escherichia coli Proteins
  • QepA protein, E coli