[Choroidal thickness assessment with SD-OCT in high myopia with dome-shaped macula]

J Fr Ophtalmol. 2014 Mar;37(3):237-41. doi: 10.1016/j.jfo.2013.10.002. Epub 2014 Feb 20.
[Article in French]


Purpose: To measure macular choroidal thickness (CT) using spectral-domain optical coherence tomography (SD-OCT) in highly myopic eyes with dome-shaped macula (DSM), and to investigate whether the choroid is thicker in these eyes compared to highly myopic eyes without MB.

Patients and methods: A cross-sectional study of 200 eyes was performed between January 2010 and June 2012. Twenty-four highly myopic eyes (12%) had a dome-shaped macula. All patients underwent a complete ophthalmological examination, SD-OCT (TOPCON 2000), and B-scan ultrasonography. OCT scans were analyzed in 7 sections, and subfoveal CT was measured manually between the Bruch's membrane and the internal aspect of the sclera. The 20 eyes with isolated dome-shaped macular were paired by age and axial length (AL) with 20 eyes without macular involvement.

Results: In the subgroup with isolated MB, the mean subfoveal CT was 101.86 μm (± 21.35 μm). A statistically significant negative correlation was found between CT and AL (r=-0.623, P=0.0001). The regression equation demonstrated a decrease of 8.3 μm per mm of AL. In the subgroup without MB, matched with the subgroup with MB by age (P=0.591), and AL (P=0.815), the mean subfoveal CT was 89.54 μm (± 20.12 μm). The comparison between the two subgroups found a statistically significant difference in subfoveal CT (P<10-4).

Conclusions: In our study, choroidal thickness is increased in highly myopic eyes with dome-shaped macula compared to highly myopic eyes without dome-shaped macula. These findings suggest that abnormalities of the choroid may play a role in the pathogenesis of dome-shaped macula.

Keywords: Choroid; Choroïde; Dome-shaped macula; High myopia; Macula bombée; Myopie forte; SD-OCT.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Choroid / pathology*
  • Cross-Sectional Studies
  • Female
  • Humans
  • Macula Lutea
  • Male
  • Middle Aged
  • Myopia / complications
  • Myopia / pathology
  • Retinal Diseases / complications
  • Retinal Diseases / pathology
  • Retrospective Studies
  • Tomography, Optical Coherence* / methods
  • Young Adult