Reoperation for neoaortic root pathology after the arterial switch operation

Eur J Cardiothorac Surg. 2014 Sep;46(3):474-9; discussion 479. doi: 10.1093/ejcts/ezu026. Epub 2014 Feb 23.


Objectives: To evaluate incidence and results of surgical intervention for neoaortic root pathology following arterial switch operation (ASO) for transposition of the great arteries (TGA).

Methods: Between April 1996 and August 2013, 12 patients underwent reoperation for neoaortic root dilatation (ARD) and/or neoaortic valve regurgitation (AR). Maximal aortic sinus and annulus diameter Z-scores were recorded. Original diagnoses were TGA/IVS (6), TGA/ventricular septal defect (VSD) (4) and Taussig-Bing anomaly (2) with ASO at a median age of 0.1 (range: 0-10.6) years. Age at ASO, VSD and complex TGA were reviewed as possible risk factors for reoperation.

Results: Twelve patients with tricuspid neoaortic valves underwent 15 root operations; indications were root dilatation (4) and root dilatation with AR (8). Median age was 18.0 (3.0-29.0) years at first reoperation. Median aortic root Z-score at reoperation was 6.33 (range: 3.84-12.15). Procedures were: Bentall procedure (6), aortic valve replacement (2), neoaortic valve plasty (1), supracoronary tube (1) and switch-back operation (2). Mean follow-up was 7.0 ± 5.7 years and complete. No mortality occurred. One patient had two reoperations for late endocarditis. Technical difficulties were encountered related to specific anatomy post-ASO concerning coronary anatomy, poor exposure and thin-walled aorta at the site of pulmonary artery bifurcation after Lecompte manoeuvre. Valve sparing surgery seemed not feasible due to specific anatomy of the neoaortic root and valve. No risk factors for reoperation could be identified.

Conclusions: After ASO, surgery for neoaortic root pathology may become necessary when follow-up is long enough and regardless of primary diagnosis or other risk factors. Redo neoaortic surgery can be performed with low risk taking into account the specific technical difficulties.

Keywords: Arterial switch operation; Neoaortic regurgitation; Neoaortic root dilatation; Reoperation; Transposition of the great arteries.

MeSH terms

  • Adolescent
  • Adult
  • Aorta / pathology
  • Aorta / surgery*
  • Aortic Valve Insufficiency / epidemiology
  • Aortic Valve Insufficiency / surgery*
  • Child
  • Child, Preschool
  • Follow-Up Studies
  • Humans
  • Infant
  • Infant, Newborn
  • Reoperation / statistics & numerical data*
  • Transposition of Great Vessels / pathology*
  • Transposition of Great Vessels / surgery*
  • Young Adult