Trial watch: global migration of clinical trials

Nat Rev Drug Discov. 2014 Mar;13(3):166-7. doi: 10.1038/nrd4260.


Defining the global migration of clinical research is central to allocating resources in coordinated efforts to address global health needs. We used 15 World Health Organization-approved clinical trial registries to measure patterns of clinical research by geographic region and development over a 14-year period. With data from 205,455 trials, we show that clinical research is shifting from high-income countries to low- and middle-income Asian countries, which has clinical, public health, regulatory, ethical, and economic implications.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Clinical Trials as Topic / methods
  • Clinical Trials as Topic / trends*
  • Global Health / trends*
  • Humans
  • Internationality*