Formation of nanostructured fluorapatite via microwave assisted solution combustion synthesis

Maryam Nabiyouni; Huan Zhou; Timothy J F Luchini; Sarit B Bhaduri

doi:10.1016/j.msec.2014.01.018

Formation of nanostructured fluorapatite via microwave assisted solution combustion synthesis

Mater Sci Eng C Mater Biol Appl. 2014 Apr 1:37:363-8. doi: 10.1016/j.msec.2014.01.018. Epub 2014 Jan 11.

Authors

Maryam Nabiyouni¹, Huan Zhou², Timothy J F Luchini³, Sarit B Bhaduri⁴

Affiliations

¹ Department of Bioengineering, The University of Toledo, Toledo, OH, USA.
² Institute of Biomedical Engineering and Health Sciences, Changzhou University, Changzhou, Jiangsu, China; Department of Mechanical, Industrial and Manufacturing Engineering, The University of Toledo, Toledo, OH, USA. Electronic address: Huan.Zhou@rockets.utoledo.edu.
³ Composite Vehicle Research Center, Michigan State University, East Lansing, MI, USA.
⁴ Department of Mechanical, Industrial and Manufacturing Engineering, The University of Toledo, Toledo, OH, USA; Division of Dentistry, The University of Toledo, Toledo, OH, USA.

PMID: 24582261
DOI: 10.1016/j.msec.2014.01.018

Abstract

Fluorapatite (FA) has potential applications in dentistry and orthopedics, but its synthesis procedures are time consuming. The goal of the present study is to develop a quick microwave assisted solution combustion synthesis method (MASCS) for the production of FA particles. With this new processing, FA particles were successfully synthesized in minutes. Additionally, unique structures including nanotubes, hexagonal crystals, nanowhiskers, and plate agglomerates were prepared by controlling the solution composition and reaction time. In particular, the as-synthesized FA nanotubes presented a "Y" shape inner channel along the crystal axis. It is supposed that the channel formation is caused by the crystal growth and removal of water soluble salts during processing. The as-synthesized FA nanotubes showed good cytocompatibility, the cells cultured with a higher FA concentration demonstrated greater growth rate. With this new and easily applied MASCS processing application, FA nanoparticles have increased potential in dental and orthopedic applications.

Keywords: Fluorapatite; Microwave assisted solution combustion synthesis; Nanotubes.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Animals
Apatites / chemistry*
Cell Line
Cell Proliferation / drug effects
Cell Survival / drug effects
Mice
Microwaves*
Nanostructures / chemistry*
Nanostructures / toxicity
Nanostructures / ultrastructure
Solutions / chemistry*

Substances

Apatites
Solutions
fluorapatite