Vector biodiversity did not associate with tick-borne pathogen prevalence in small mammal communities in northern and central California

Ticks Tick Borne Dis. 2014 Apr;5(3):299-304. doi: 10.1016/j.ttbdis.2013.12.003. Epub 2014 Feb 25.

Abstract

Vector and host abundance affect infection transmission rates, prevalence, and persistence in communities. Biological diversity in hosts and vectors may provide "rescue" hosts which buffer against pathogen extinction and "dilution" hosts which reduce the force of infection in communities. Anaplasma phagocytophilum is a tick-transmitted zoonotic pathogen that circulates in small mammal and tick communities characterized by varying levels of biological diversity. We examined the prevalence of A. phagocytophilum in Ixodes spp. ticks in 11 communities in northern and central California. A total of 1020 ticks of 8 species was evaluated. Five percent of ticks (5 species) were PCR-positive, with the highest prevalence (6-7%) in I. pacificus and I. ochotonae. In most species, adults had a higher prevalence than nymphs or larvae. PCR prevalence varied between 0% and 40% across sites; the infection probability in ticks increased with infestation load and prevalence in small mammals, but not tick species richness, diversity, evenness, or small mammal species richness. No particular tick species was likely to "rescue" infection in the community; rather the risk of A. phagocytophilum infection is related to exposure to particular tick species and life stages, and overall tick abundance.

Keywords: Amplification effect; Dilution effect; Granulocytic anaplasmosis; Rescue effect.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Anaplasma phagocytophilum / genetics
  • Anaplasma phagocytophilum / isolation & purification*
  • Animals
  • Arachnid Vectors / microbiology*
  • Biodiversity
  • California / epidemiology
  • DNA, Bacterial / genetics
  • Ehrlichiosis / epidemiology
  • Ehrlichiosis / microbiology*
  • Female
  • Humans
  • Insectivora / microbiology*
  • Ixodes / microbiology*
  • Larva
  • Male
  • Nymph
  • Prevalence
  • Rodent Diseases / microbiology*
  • Rodentia
  • Zoonoses

Substances

  • DNA, Bacterial