Cognitive impairment in chronic kidney disease: keep vascular disease in mind

Kidney Int. 2014 Mar;85(3):505-7. doi: 10.1038/ki.2013.437.


Cognitive impairment is a major cause of morbidity in people with chronic kidney disease (CKD) and is associated with worse survival. Prior data suggest a relationship between vascular disease and cognitive impairment in individuals with CKD. Clinicians should be aware of the high rates of cognitive impairment that occur in all stages of CKD, which, although sometimes subtle, may impact comprehension and decision making and may herald future, more debilitating impairment.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Cognition Disorders / blood*
  • Female
  • Fibrinogen / analysis*
  • Glycated Hemoglobin A / analysis*
  • Humans
  • Male
  • Renal Insufficiency, Chronic / blood*


  • Glycated Hemoglobin A
  • hemoglobin A1c protein, human
  • Fibrinogen