Objective: To estimate whether there is an association between cesarean delivery and the subsequent development ofadenomyosis uteri based on pathologic diagnosis.
Study design: A total of 601 patients who had had a hysterectomy at a community hospital were identified. Data were collected from their medical records, focusing on uterine pathology and prior obstetric history. These data formed the basis for a case-control study to disclose an association between cesarean delivery and the subsequent development of adenomyosis uteri.
Results: Among 189 women with adenomyosis, cesarean delivery had occurred in 25%. This contrasted with 14% cesarean deliveries among those 178 women without adenomyosis, for an odds ratio of 2.08. These 2 groups were comparable in make-up in regard to demographic variables and medical history.
Conclusion: There is strong association between adenomyosis and previous cesarean section. This association raises important questions about whether technical aspects of cesarean section may contribute to the consequence of adenomyosis.