Practical approach to implementing dietary therapy in adults with eosinophilic esophagitis: the Chicago experience

Dis Esophagus. 2015 Jan;28(1):42-58. doi: 10.1111/dote.12175. Epub 2014 Mar 6.


Eosinophilic esophagitis (EoE) is a chronic immune/antigen-mediated esophageal disease characterized by esophageal dysfunction and esophageal mucosal eosinophilia. Diet therapy is effective in the treatment of EoE in both children and adults. The role of food allergens is well established in the pathogenesis and treatment of eosinophilic esophagitis. Empiric elimination with a six-food elimination diet (avoiding milk, wheat, egg, soy, peanuts/tree nuts, and fish/shellfish) demonstrates remission in over 70% of adults with this disease. Dietary therapy in adult EoE is becoming more accepted by both patients and clinicians. Dietary therapy can be effectively implemented in clinical practice with appropriate dietary education, patient resources, and close communication with physician and clinical staff. The ability to identify specific food triggers to help tailor dietary therapy for long-term management allows for a return to consumption of most table foods. Furthermore, the diet approach avoids the need for chronic topical corticosteroid use and possible long-term side effects of these medications. The decision to proceed with dietary therapy should be decided by patient preference and available resources. A collaborative and multidisciplinary approach including gastroenterologists, allergists, nurses, and dietitians is essential in the success of this approach.

Keywords: dietary therapy; dysphagia; eosinophilic esophagitis; nutrition assessment.

Publication types

  • Review

MeSH terms

  • Adult
  • Chicago
  • Eosinophilic Esophagitis / diet therapy*
  • Eosinophilic Esophagitis / etiology
  • Food Hypersensitivity / complications
  • Food Hypersensitivity / diet therapy*
  • Humans