Challenges in the management of infections due to carbapenem-resistant Enterobacteriaceae

Infect Control Hosp Epidemiol. 2014 Apr;35(4):437-9. doi: 10.1086/675604.


Carbapenem-resistant Enterobacteriaceae (CRE) infections are increasing and are associated with considerable morbidity and mortality. Members of the Emerging Infections Network treating CRE encountered difficulties in obtaining laboratory results and struggled with limited treatment options. In addition, many treated patients experienced an alarming degree of drug toxicity from CRE therapies.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Carbapenems / pharmacology
  • Carbapenems / therapeutic use*
  • Drug Resistance, Bacterial*
  • Enterobacteriaceae / drug effects*
  • Enterobacteriaceae Infections / drug therapy*
  • Female
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Surveys and Questionnaires


  • Carbapenems