Liquid paraffin is superior to 2% lidocaine gel in reducing urethral pain during urodynamic study in men: A pilot study

Neurourol Urodyn. 2015 Jun;34(5):450-3. doi: 10.1002/nau.22581. Epub 2014 Mar 9.

Abstract

Aims: To compare the pain perception between intraurethral instillation of 2% lidocaine gel and liquid paraffin during Urodynamic study in men.

Methods: A randomized, single-blind comparison trial was conducted. Forty men scheduled to undergo multichannel Urodynamic study were randomized to receive either 10 ml of 2% lidocaine gel (group 1, n = 20) or 10 ml of liquid paraffin (group 2, n = 20). Patients recorded their pain on a 0-10 visual analog scale prior to lubricant instillation, immediately after lubricant instillation, after the introduction of the Urodynamic catheter, 5 and 30 min after the catheter was taken out.

Results: pain scores were significantly higher in group 1 compared to group 2 immediately after the instillation of the lubricants (4.2 ± 1.5 vs. 2.6 ± 0.9, P < 0.001) and after catheterization (4.8 ± 1.5 vs. 3.5 ± 1.1, P < 0.01). There were no differences in the pain scores between the two groups in the other time points that were evaluated.

Conclusions: Liquid paraffin is more efficient than 2% lidocaine gel in reducing urethral pain during Urodynamic study in men. Pain scores were specifically better during the instillation of the lubricant and during the delivery of the urethral catheter.

Keywords: lidocaine; liquid; men; pain; paraffin; urodynamics.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Administration, Topical
  • Aged
  • Aged, 80 and over
  • Anesthetics, Local / therapeutic use*
  • Diagnostic Techniques, Urological
  • Emollients / therapeutic use*
  • Gels
  • Humans
  • Lidocaine / therapeutic use*
  • Lubricants / therapeutic use*
  • Male
  • Middle Aged
  • Mineral Oil / therapeutic use*
  • Pain / prevention & control*
  • Pain Measurement
  • Pilot Projects
  • Single-Blind Method
  • Urethra
  • Urinary Catheterization / methods*
  • Urodynamics*
  • Visual Analog Scale

Substances

  • Anesthetics, Local
  • Emollients
  • Gels
  • Lubricants
  • Mineral Oil
  • Lidocaine