Pneumocystis and Pneumocystosis: first meeting of experts from Latin-American and Portuguese-speaking countries - a mini-review

Expert Rev Anti Infect Ther. 2014 May;12(5):545-8. doi: 10.1586/14787210.2014.894883. Epub 2014 Mar 11.

Abstract

The Pneumocystis and Pneumocystosis: first meeting of experts from Latin-American and Portuguese-speaking countries was held in Lisbon, Portugal, on 24-26 October 2013. A total of 20 speakers from Latin America, Africa and Europe participated in the meeting. The epidemiological studies presented in this meeting begin to change the misconception that since the AIDS epidemic, Pneumocystis pneumonia (PcP) has become an infrequent disease, showing that today PcP remains a major opportunistic infection in HIV-infected patients in both developed and developing countries and an emerging problem in immunocompromised patients without HIV infection worldwide. PcP management remains a challenge. Right now, the combination of caspofungin and trimethoprim-sulfamethoxazole (TMP-SMX) is a promising therapeutic approach that needs to be assessed in controlled clinical trials.

Publication types

  • Congress

MeSH terms

  • AIDS-Related Opportunistic Infections / drug therapy*
  • AIDS-Related Opportunistic Infections / immunology*
  • AIDS-Related Opportunistic Infections / microbiology
  • AIDS-Related Opportunistic Infections / virology
  • Anti-Infective Agents / therapeutic use*
  • Caspofungin
  • Developed Countries
  • Developing Countries
  • Echinocandins / therapeutic use
  • Humans
  • Immunocompromised Host*
  • Latin America
  • Lipopeptides
  • Pneumocystis carinii / drug effects
  • Pneumocystis carinii / pathogenicity
  • Pneumocystis carinii / physiology
  • Pneumonia, Pneumocystis / drug therapy*
  • Pneumonia, Pneumocystis / immunology*
  • Pneumonia, Pneumocystis / microbiology
  • Pneumonia, Pneumocystis / virology
  • Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use

Substances

  • Anti-Infective Agents
  • Echinocandins
  • Lipopeptides
  • Trimethoprim, Sulfamethoxazole Drug Combination
  • Caspofungin