ASIA or Shoenfeld's syndrome--an autoimmune syndrome induced by adjuvants

Rom J Intern Med. Jul-Dec 2013;51(3-4):131-4.

Abstract

Recently, reports have suggested grouping different autoimmune conditions that are triggered by external stimuli as a single syndrome called autoimmune syndrome induced by adjuvants (ASIA). This syndrome is characterized by the appearance of myalgia, myositis, muscle weakness, arthralgia, arthritis, chronic fatigue, sleep disturbances, cognitive impairment and memory loss, and the possible emergence of a demyelinating autoimmune disease caused by systemic exposure after vaccines and adjuvants. As there are no markers for ASIA, the authors intend to present ASIA, or Shoenfeld's syndrome, as an autoimmune syndrome induced by adjuvants.

Publication types

  • Review

MeSH terms

  • Adjuvants, Pharmaceutic / adverse effects*
  • Arthralgia / immunology
  • Arthritis / immunology
  • Autoimmune Diseases / chemically induced*
  • Autoimmune Diseases / epidemiology
  • Autoimmune Diseases / immunology*
  • Biomarkers / metabolism
  • Cognition Disorders / immunology
  • Fatigue / immunology
  • HLA-DRB1 Chains / immunology*
  • Humans
  • Inflammation / immunology
  • Memory Disorders / immunology
  • Muscle Weakness / immunology
  • Myalgia / immunology
  • Myositis / immunology
  • Romania / epidemiology
  • Silicones / adverse effects
  • Sleep Wake Disorders / immunology
  • Syndrome
  • Vaccines / adverse effects*

Substances

  • Adjuvants, Pharmaceutic
  • Biomarkers
  • HLA-DRB1 Chains
  • Silicones
  • Vaccines