Oral rivaroxaban for the treatment of symptomatic pulmonary embolism: are we ready?

CJEM. 2014 Mar;16(2):155-7. doi: 10.2310/8000.2013.131073.

Abstract

Clinical question: Can an oral regimen of rivaroxaban be used for the treatment of symptomatic pulmonary embolism?

Article chosen: Büller H, Prins M, Lensing A, et al. Oral rivaroxaban for the treatment of symptomatic pulmonary embolism. N Engl J Med 2012;366:1287-97.

Objective: To determine the effectiveness and safety of oral rivaroxaban in the treatment of symptomatic pulmonary embolism when compared to current standard therapy.

Publication types

  • Comment

MeSH terms

  • Anticoagulants / therapeutic use*
  • Female
  • Humans
  • Male
  • Morpholines / therapeutic use*
  • Pulmonary Embolism / drug therapy*
  • Thiophenes / therapeutic use*

Substances

  • Anticoagulants
  • Morpholines
  • Thiophenes