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, 46 (6), 1583-7

L-Theanine Elicits Umami Taste via the T1R1 + T1R3 Umami Taste Receptor

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L-Theanine Elicits Umami Taste via the T1R1 + T1R3 Umami Taste Receptor

Masataka Narukawa et al. Amino Acids.

Abstract

L-Theanine is a unique amino acid present in green tea. It elicits umami taste and has a considerable effect on tea taste and quality. We investigated L-theanine activity on the T1R1 + T1R3 umami taste receptor. L-Theanine activated T1R1 + T1R3-expressing cells and showed a synergistic response with inosine 5'-monophosphate. The site-directed mutagenesis analysis revealed that L-theanine binds to L-amino acid binding site in the Venus flytrap domain of T1R1. This study shows that L-theanine elicits an umami taste via T1R1 + T1R3.

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