Navigating and mining modENCODE data

Methods. 2014 Jun 15;68(1):38-47. doi: 10.1016/j.ymeth.2014.03.007. Epub 2014 Mar 15.

Abstract

modENCODE was a 5year NHGRI funded project (2007-2012) to map the function of every base in the genomes of worms and flies characterizing positions of modified histones and other chromatin marks, origins of DNA replication, RNA transcripts and the transcription factor binding sites that control gene expression. Here we describe the Drosophila modENCODE datasets and how best to access and use them for genome wide and individual gene studies.

Keywords: Chromatin; Drosophila; Mining; Transcription; modENCODE.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Chromatin / genetics
  • DNA Replication / genetics*
  • Data Mining
  • Databases, Genetic*
  • Developmental Biology / methods*
  • Drosophila melanogaster / genetics
  • Drosophila melanogaster / growth & development
  • Genome, Insect

Substances

  • Chromatin