Ethyl alcohol and the products of its metabolism influence changes in the functioning of numerous tissues and organs, as well as enzymes and hormones. Alcohol causes malfunction of the hormonal pivot hypothalamus--pituitary gland--adrenal glands and hypothalamus-pituitary gland--thyroid, alcohol is harmful to the functioning of gonads and causes dysfunction of parathyroid. Long-term abuse of alcohol causes degeneration of liver cells, which results in carbohydrate disorders. Among people who consume excessive amounts of alcohol, there are higher risks of type 2 diabetes, secondary diabetes and chronic pancreatitis as a result of the damage of the pancreatic islands B.