Optic chiasm involvement on MRI with ethambutol-induced bitemporal hemianopia

J Neuroophthalmol. 2014 Jun;34(2):155-8. doi: 10.1097/WNO.0000000000000095.


While ethambutol optic neuropathy usually causes central or cecocentral scotomas, bitemporal visual field defects also have been reported. The pathogenesis of the bitemporal hemianopia has not been established. This article describes magnetic resonance imaging abnormalities involving the optic chiasm in a patient with bitemporal visual field loss. To our knowledge, these neuroimaging findings have not been previously described in association with ethambutol therapy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antitubercular Agents / adverse effects*
  • Ethambutol / adverse effects*
  • Female
  • Hemianopsia / chemically induced*
  • Hemianopsia / pathology*
  • Humans
  • Magnetic Resonance Imaging
  • Optic Chiasm / pathology*
  • Visual Acuity / drug effects


  • Antitubercular Agents
  • Ethambutol