Biofilm matrix-degrading enzymes

Methods Mol Biol. 2014;1147:203-13. doi: 10.1007/978-1-4939-0467-9_14.


Polymeric substances such as proteins, polysaccharides, and DNA constitute a major component of the biofilm matrix. Enzymes that depolymerize and degrade these components are useful tools for investigating the composition and function of the biofilm matrix. This chapter provides a brief overview of the most commonly used biofilm matrix-degrading enzymes and presents examples of their applications in biofilm research.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Physiological Phenomena
  • Biofilms*
  • Extracellular Matrix / chemistry
  • Extracellular Matrix / metabolism*
  • Plankton / physiology