Predictors of future health-related quality of life in survivors of adolescent cancer

Pediatr Blood Cancer. 2014 Oct;61(10):1891-4. doi: 10.1002/pbc.25037. Epub 2014 Mar 24.


The purpose of this study was to identify characteristics associated with health-related quality of life (HRQOL) among long-term survivors of adolescent cancer enrolled in the Childhood Cancer Survivor Study. Thirty percent of survivors reported poor physical and/or mental HRQOL. Race/ethnicity, education, and head/neck disfigurement were significantly associated with poor mental HRQOL, while sex, age, household income, obesity, alkylating agents, pelvic radiation, head/neck or limb disfigurement, and walking with a limp were associated with poor physical HRQOL. Identification of high-risk adolescent cancer patients may facilitate timely intervention to attempt to minimize the impact of cancer and treatment on subsequent quality of life.

Keywords: adolescent cancer survivor; quality of life.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age of Onset
  • Female
  • Health Status*
  • Humans
  • Male
  • Middle Aged
  • Neoplasms / psychology*
  • Quality of Life*
  • Surveys and Questionnaires
  • Survivors / psychology*