Streptococcus suis infection: an emerging/reemerging challenge of bacterial infectious diseases?

Virulence. 2014 May 15;5(4):477-97. doi: 10.4161/viru.28595. Epub 2014 Mar 25.


Streptococcus suis (S. suis) is a family of pathogenic gram-positive bacterial strains that represents a primary health problem in the swine industry worldwide. S. suis is also an emerging zoonotic pathogen that causes severe human infections clinically featuring with varied diseases/syndromes (such as meningitis, septicemia, and arthritis). Over the past few decades, continued efforts have made significant progress toward better understanding this zoonotic infectious entity, contributing in part to the elucidation of the molecular mechanism underlying its high pathogenicity. This review is aimed at presenting an updated overview of this pathogen from the perspective of molecular epidemiology, clinical diagnosis and typing, virulence mechanism, and protective antigens contributing to its zoonosis.

Keywords: Streptococcus suis; pathogenesis; zoonosis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Communicable Diseases, Emerging / microbiology*
  • Communicable Diseases, Emerging / transmission
  • Humans
  • Streptococcal Infections / microbiology*
  • Streptococcal Infections / transmission
  • Streptococcal Infections / veterinary*
  • Streptococcus suis / genetics
  • Streptococcus suis / isolation & purification
  • Streptococcus suis / physiology*
  • Swine
  • Swine Diseases / microbiology*
  • Zoonoses / microbiology*
  • Zoonoses / transmission