Enantioselective synthesis and enhanced circularly polarized luminescence of S-shaped double azahelicenes

J Am Chem Soc. 2014 Apr 16;136(15):5555-8. doi: 10.1021/ja500841f. Epub 2014 Apr 4.


The enantioselective synthesis of azahelicenes and S-shaped double azahelicenes has been achieved via the Au-catalyzed sequential intramolecular hydroarylation of alkynes. The use of excess AgOTf toward a Au(I) complex is crucial for this transformation. Interestingly, the circularly polarized luminescence activity of the S-shaped double azahelicenes was significantly higher than that of the azahelicenes.