Bilateral acute iris transillumination following a fumigation therapy: a village-based traditional method for the treatment of ophthalmomyiasis

Cutan Ocul Toxicol. 2015 Mar;34(1):80-3. doi: 10.3109/15569527.2014.886589. Epub 2014 Mar 31.


Bilateral acute iris transillumination (BAIT) is a relatively new clinical entity characterized by bilateral acute loss of iris pigment epithelium, iris transillumination, pigment dispersion in the anterior chamber and atonic pupilla. We report herein a 50-year-old female who presented with bilateral ocular pain, severe photophobia and red eyes. One month ago, a fly hit her eye, and she instantly complained of a discomfort and sensation of a foreign body in both eyes. She used a fumigation therapy, a traditional method for the treatment of ophthalmomyiasis. During follow-up examinations, intraocular pressures increased over 40 mmHg bilaterally despite maximal medical therapy, which necessitated trabeculectomy surgery with mitomycin. This is a typical BAIT case with no antecedent fluoroquinolone use or viral disease, but a fumigation therapy. There might be a possible relationship between BAIT and traditional fumigation therapy or this association might be coincidental, both of which need further evaluation.

Keywords: Atonic papilla; BAIT; fumigation therapy; iris transillumination; mydriasis; pigment dispersion.

Publication types

  • Case Reports

MeSH terms

  • Berberis
  • Female
  • Fumigation*
  • Humans
  • Iris Diseases / diagnosis*
  • Iris Diseases / etiology*
  • Medicine, Traditional
  • Middle Aged
  • Seeds
  • Smoke*


  • Smoke