Psychiatric disorders: diagnosis to therapy

Cell. 2014 Mar 27;157(1):201-14. doi: 10.1016/j.cell.2014.02.042.


Recent findings in a range of scientific disciplines are challenging the conventional wisdom regarding the etiology, classification, and treatment of psychiatric disorders. This Review focuses on the current state of the psychiatric diagnostic nosology and recent progress in three areas: genomics, neuroimaging, and therapeutics development. The accelerating pace of novel and unexpected findings is transforming the understanding of mental illness and represents a hopeful sign that the approaches and models that have sustained the field for the past 40 years are yielding to a flood of new data and presaging the emergence of a new and more powerful scientific paradigm.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Humans
  • Mental Disorders / classification
  • Mental Disorders / diagnosis*
  • Mental Disorders / genetics
  • Mental Disorders / therapy*
  • Neuroimaging
  • Neurosciences / methods*