The neural changes in connectivity of the voice network during voice pitch perturbation

Brain Lang. 2014 May;132:7-13. doi: 10.1016/j.bandl.2014.02.001. Epub 2014 Mar 27.

Abstract

Voice control is critical to communication. To date, studies have used behavioral, electrophysiological and functional data to investigate the neural correlates of voice control using perturbation tasks, but have yet to examine the interactions of these neural regions. The goal of this study was to use structural equation modeling of functional neuroimaging data to examine network properties of voice with and without perturbation. Results showed that the presence of a pitch shift, which was processed as an error in vocalization, altered connections between right STG and left STG. Other regions that revealed differences in connectivity during error detection and correction included bilateral inferior frontal gyrus, and the primary and pre motor cortices. Results indicated that STG plays a critical role in voice control, specifically, during error detection and correction. Additionally, pitch perturbation elicits changes in the voice network that suggest the right hemisphere is critical to pitch modulation.

Keywords: Connectivity; Error detection and correction; Sparse sampling; Structural equation modeling; Voice control; fMRI.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Brain Mapping / methods
  • Cerebral Cortex / physiology*
  • Feedback, Physiological / physiology*
  • Functional Neuroimaging / methods
  • Humans
  • Magnetic Resonance Imaging / methods
  • Male
  • Models, Neurological*
  • Motor Cortex / physiology
  • Nerve Net / physiology
  • Pitch Discrimination / physiology*
  • Pitch Perception / physiology
  • Prefrontal Cortex / physiology
  • Temporal Lobe / physiology
  • Voice / physiology*