Addressing the confounding role of joint hypermobility syndrome and gastrointestinal involvement in postural orthostatic tachycardia syndrome

Clin Auton Res. 2014 Jun;24(3):157-8. doi: 10.1007/s10286-014-0239-9. Epub 2014 Mar 29.


Quantitative and qualitative abnormalities in visceral function have been demonstrated in postural orthostatic tachycardia syndrome. Joint hypermobility is frequently associated with both postural orthostatic tachycardia syndrome and gastrointestinal symptoms. Future studies in this area should appropriately and systematically control for the presence of joint hypermobility syndrome.

MeSH terms

  • Gastrointestinal Tract / pathology*
  • Humans
  • Joint Instability / complications*
  • Joint Instability / pathology
  • Postural Orthostatic Tachycardia Syndrome / complications*
  • Postural Orthostatic Tachycardia Syndrome / diagnosis
  • Postural Orthostatic Tachycardia Syndrome / pathology
  • Tilt-Table Test