Bioactivity of cedarwood oil and cedrol against arthropod pests

Environ Entomol. 2014 Jun;43(3):762-6. doi: 10.1603/EN13270. Epub 2014 Mar 31.


Heartwood samples from Juniperus virginiana L. were extracted with liquid carbon dioxide, and the bioactivity of carbon dioxide-derived cedarwood oil (CWO) toward several species of ants and cedrol toward ticks was determined. Repellency was tested for ants, and toxicity was tested for ticks. Ants in an outdoor bioassay were significantly repelled by the presence of CWO on a pole leading to a sugar-water solution. Similarly, CWO was a significant repellent barrier to red imported fire ants and prevented them from finding a typical food source. Black-legged tick nymphs exhibited dosage-dependent mortality when exposed to cedrol and at the highest dosage (i.e., 6.3 mg/ml) tested, the cedrol killed 100% of the ticks. These repellency and toxicity results together demonstrate a clear potential for the use of CWO as a pest control agent.

MeSH terms

  • Acaricides*
  • Animals
  • Ants*
  • Dose-Response Relationship, Drug
  • Insect Control*
  • Insect Repellents*
  • Ixodes* / growth & development
  • Nymph
  • Oils, Volatile*
  • Polycyclic Sesquiterpenes
  • Species Specificity
  • Terpenes*


  • Acaricides
  • Insect Repellents
  • Oils, Volatile
  • Polycyclic Sesquiterpenes
  • Terpenes
  • cedrol
  • cedarwood oil