Journey to the center of the centrosome

Dev Cell. 2014 Mar 31;28(6):603-4. doi: 10.1016/j.devcel.2014.03.011.

Abstract

Little is understood about how the centrosome, a complex organelle and signaling hub consisting of hundreds of components, is assembled. In this issue of Developmental Cell, Conduit et al. (2014) shed light on this issue, showing that modification and recruitment of Centrosomin to the centrosome center creates a dynamic pericentriolar matrix.

Publication types

  • Comment

MeSH terms

  • Animals
  • Cell Cycle Proteins / metabolism*
  • Centrosome / metabolism*
  • Drosophila Proteins / metabolism*
  • Drosophila melanogaster / metabolism*
  • Homeodomain Proteins / metabolism*
  • Mitosis / physiology*
  • Polo-Like Kinase 1
  • Protein Serine-Threonine Kinases / metabolism*
  • Proto-Oncogene Proteins / metabolism*

Substances

  • Cell Cycle Proteins
  • Drosophila Proteins
  • Homeodomain Proteins
  • Proto-Oncogene Proteins
  • cnn protein, Drosophila
  • polo protein, Drosophila
  • Protein Serine-Threonine Kinases