Non-motor Parkinson's: Integral to Motor Parkinson's, Yet Often Neglected

Pract Neurol. 2014 Oct;14(5):310-22. doi: 10.1136/practneurol-2013-000741. Epub 2014 Apr 3.

Abstract

Non-motor symptoms are a key component of Parkinson's disease, possibly representing a clinical biomarker of its premotor phase. The burden of non-motor symptoms can define a patient's health-related quality of life. Non-motor symptoms substantially increase the cost of care-requiring increased hospitalisation and treatment-and pose a major challenge to healthcare professionals. However, clinicians often regard non-motor symptoms and their management as peripheral to that of the motor symptoms. Here, we address the clinical issues and unmet needs of non-motor symptoms in Parkinson's disease.

Keywords: NMSQuest; NON MOTOR SYMPTOMS; PARKINSON'S DISEASE.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antiparkinson Agents / adverse effects
  • Humans
  • Parkinson Disease / complications*
  • Parkinson Disease / drug therapy
  • Parkinson Disease / epidemiology
  • Parkinson Disease / psychology
  • Quality of Life
  • Severity of Illness Index

Substances

  • Antiparkinson Agents