Bilateral surgical reconstruction for internal jugular veins disease in patients with chronic cerebrospinal venous insufficiency and associated multiple sclerosis

Ann Vasc Surg. 2014 Oct;28(7):1793.e1-4. doi: 10.1016/j.avsg.2014.03.012. Epub 2014 Apr 2.


Chronic cerebrospinal venous insufficiency (CCSVI) is a vascular condition characterized by morphologic alterations involving efferent cerebral vascular paths. CCSVI has been implicated as a contributing factor to multiple sclerosis (MS) but this theory is highly controversial. We report 3 cases of CCSVI patients with MS who had undergone internal jugular veins (IJVs) angioplasty to restore vessels patency. All patients reported significant symptomatic improvement after angioplasty until symptoms recurred after restenosis of the treated IJVs. Surgical IJVs reconstruction was performed. Patients' symptoms gradually improved and the benefits were maintained at the 1-year follow-up.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cerebrovascular Disorders / complications
  • Cerebrovascular Disorders / surgery*
  • Chronic Disease
  • Humans
  • Jugular Veins / surgery*
  • Male
  • Multiple Sclerosis, Relapsing-Remitting / complications*
  • Saphenous Vein / transplantation*
  • Vascular Patency
  • Vascular Surgical Procedures / methods*
  • Venous Insufficiency / complications
  • Venous Insufficiency / surgery*