Peptide-perylene diimide functionalized magnetic nano-platforms for fluorescence turn-on detection and clearance of bacterial lipopolysaccharides

Chem Commun (Camb). 2014 Jun 14;50(47):6200-3. doi: 10.1039/c4cc01266f. Epub 2014 Apr 7.

Abstract

A simple and unique strategy has been successfully designed for sensitive detection and rapid clearance of bacterial lipopolysaccharides (LPS) by integration of core-shell Fe3O4@SiO2 magnetic nanoparticles with a perylene-diimide (PDI) conjugated LPS-recognition peptide.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bacteria / chemistry
  • Cell Line
  • Fluorescence*
  • Imides / chemistry*
  • Lipopolysaccharides / chemistry*
  • Magnetite Nanoparticles / chemistry*
  • Mice
  • Peptides / chemistry*
  • Perylene / analogs & derivatives*
  • Perylene / chemistry

Substances

  • Imides
  • Lipopolysaccharides
  • Magnetite Nanoparticles
  • Peptides
  • perylenediimide
  • Perylene