[Role of the Rho-kinase pathway in pulmonary arterial hypertension]

MeSH terms

• 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine / analogs & derivatives*
• 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine / pharmacology
• 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine / therapeutic use
• Animals
• Bosentan
• Drug Therapy, Combination
• Epoprostenol / analogs & derivatives
• Epoprostenol / therapeutic use
• Humans
• Hypertension, Pulmonary / diagnosis
• Hypertension, Pulmonary / drug therapy*
• Hypertension, Pulmonary / genetics*
• Hypertension, Pulmonary / physiopathology
• Mice
• Molecular Targeted Therapy*
• Piperazines / therapeutic use
• Protein Kinase Inhibitors / pharmacology*
• Protein Kinase Inhibitors / therapeutic use*
• Purines / therapeutic use
• Rats
• Signal Transduction / drug effects
• Signal Transduction / genetics*
• Signal Transduction / physiology*
• Sildenafil Citrate
• Sulfonamides / therapeutic use
• Sulfones / therapeutic use
• Vascular Resistance / drug effects
• rho-Associated Kinases / antagonists & inhibitors*
• rho-Associated Kinases / physiology*