New and emerging treatments for hyperpigmentation

J Drugs Dermatol. 2014 Apr;13(4):382-5.

Abstract

The treatment of disorders of hyperpigmentation including melasma, photoaging-related dyschromia, and postinflammatory hyperpigmentation pose numerous challenges, especially in patients with higher Fitzpatrick skin types (skin of color). Given limitations in efficacy as well as safety and cost considerations of available therapies, a "magic bullet" single treatment modality for hyperpigmentation is currently lacking. Successful treatment typically involves a combination of topical agents with or without in-office procedures, exploiting the different mechanisms of action of each agent or treatment modality. This article will review recently published studies involving newer topical and procedural approaches to this common dermatologic concern.

Publication types

  • Review

MeSH terms

  • Administration, Cutaneous
  • Drug Therapy, Combination
  • Enzyme Inhibitors / administration & dosage
  • Humans
  • Hydroquinones / administration & dosage
  • Hyperpigmentation / drug therapy*
  • Hyperpigmentation / therapy
  • Lasers, Solid-State / therapeutic use*
  • Phytotherapy*
  • Plant Preparations / administration & dosage
  • Skin Lightening Preparations / administration & dosage*

Substances

  • Enzyme Inhibitors
  • Hydroquinones
  • Plant Preparations
  • Skin Lightening Preparations
  • hydroquinone