Nephrotic syndrome redux

Nephrol Dial Transplant. 2015 Jan;30(1):12-7. doi: 10.1093/ndt/gfu077. Epub 2014 Apr 10.


Redux: brought back, resurgent (Wikipedia free dictionary). This essay traces the history of the concepts that led to the usage of the term 'nephrotic syndrome' beginning ∼90 years ago. We then examined the various definitions used for this syndrome and modified them to conform to contemporary standards. Remarkably, only minor modifications were required. This analysis of a common clinical entity may be helpful in ensuring appropriate evaluation of patients suffering from nephrotic syndrome and nephrotic-range proteinuria.

Keywords: nephrosis; nephrotic syndrome; nephrotic-range proteinuria.

Publication types

  • Historical Article

MeSH terms

  • History, 20th Century
  • History, 21st Century
  • Humans
  • Nephrotic Syndrome / diagnosis
  • Nephrotic Syndrome / history*
  • Proteinuria / history