In vitro uptake of apoptotic body mimicking phosphatidylserine-quantum dot micelles by monocytic cell line

Nanoscale Res Lett. 2014 Apr 11;9(1):176. doi: 10.1186/1556-276X-9-176. eCollection 2014.


A new quantum dot (QD) PEGylated micelle laced with phosphatidylserine (PS) for specific scavenger receptor-mediated uptake by macrophages is reported. The size and surface chemistry of PS-QD micelles were characterized by standard methods and the effects of their physicochemical properties on specific targeting and uptake were comprehensively studied in a monocytic cell line (J774A.1).

Keywords: Macrophages; Micelles; Phosphatidylserine; Quantum dots.