Therapeutic applications of repetitive transcranial magnetic stimulation (rTMS) in movement disorders: a review

Parkinsonism Relat Disord. 2014 Jul;20(7):695-707. doi: 10.1016/j.parkreldis.2014.03.018. Epub 2014 Mar 28.

Abstract

Repetitive transcranial magnetic stimulation (rTMS) is emerging as a valuable adjunctive therapeutic modality in movement disorders. It is a non-invasive technique of repeated stimulation of the cerebral cortex by a train of magnetic pulses. The therapeutic effect of rTMS was first noted in depression. Later several researchers have investigated the role of rTMS in various movement disorders, notably Parkinson's disease, dystonia, Tourette's syndrome etc. The rTMS protocols used in these studies vary widely, lacks uniformity and often the results are not consistent. The optimal rTMS parameters for each disorder are yet to be established. This review discusses the current knowledge on the therapeutic applications of rTMS in various movement disorders.

Keywords: Cortical excitability; Intracortical facilitation; Intracortical inhibition; Motor evoked potential; Repetitive transcranial magnetic stimulation; Silent period.

Publication types

  • Review

MeSH terms

  • Animals
  • Evoked Potentials, Motor / physiology*
  • Humans
  • Motor Cortex / physiology*
  • Movement Disorders / diagnosis
  • Movement Disorders / physiopathology*
  • Movement Disorders / therapy*
  • Randomized Controlled Trials as Topic / methods
  • Transcranial Magnetic Stimulation / methods*