Effect of surgery for endometrioma on ovarian function: a different point of view

J Minim Invasive Gynecol. Jul-Aug 2014;21(4):531-3. doi: 10.1016/j.jmig.2014.03.022. Epub 2014 Apr 12.


Recent evidence in the literature suggests that surgical excision of the endometrioma wall may reduce ovarian reserve, which may have a negative effect on subsequent reproductive function. However, because of inconsistent results and methodologic flaws of anti-müllerian hormone (AMH) as a marker of ovarian reserve, antral follicle count may be a more accurate noninvasive marker than AMH. Evaluating ovarian reserve using antral follicle count rather than AMH may yield different conclusions insofar as postsurgical damage to the ovary. Surgery should be performed only by experienced surgeons, and the stripping technique currently is still the only one supported by strong scientific evidence. The dual function of surgery, that is, to improve fertility and reduce pain, cannot be minimized or undervalued.

Keywords: Endometrioma; Endometriosis; Laparoscopy; Ovarian reserve.

MeSH terms

  • Anti-Mullerian Hormone / blood*
  • Biomarkers
  • Endometriosis / surgery*
  • Female
  • Gynecologic Surgical Procedures / adverse effects*
  • Humans
  • Infertility, Female / blood
  • Infertility, Female / etiology*
  • Laparoscopy
  • Ovarian Diseases / surgery*
  • Ovarian Follicle / diagnostic imaging*
  • Ovarian Reserve
  • Ovary / diagnostic imaging
  • Ovary / surgery*
  • Ultrasonography


  • Biomarkers
  • Anti-Mullerian Hormone