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Review
, 10 (5), 152-7

DNA----DNA, and DNA----RNA----protein: Orchestration by a Single Complex Operon

Review

DNA----DNA, and DNA----RNA----protein: Orchestration by a Single Complex Operon

J R Lupski et al. Bioessays.

Abstract

In Escherichia coli, the workhorse of molecular biology, a single operon is involved in the replication, transcription and translation of genetic information. This operon is controlled in a complex manner involving multiple cis-acting regulatory sequences and trans-acting regulatory proteins. It interacts with global regulatory networks by mechanisms which are presently being dissected.

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