Effect of 2 herbal intramammary products on milk quantity and quality compared with conventional and no dry cow therapy

J Dairy Sci. 2014;97(6):3509-22. doi: 10.3168/jds.2013-7460. Epub 2014 Apr 14.


Dry cow therapy, administered at the end of lactation, is aimed at eliminating current and preventing future intramammary (IMM) bacterial infections and typically involves intramammary administration of antibiotics. Certified organic dairies in the United States are restricted from using antibiotics and must consider an alternative therapy or no dry cow therapy. The current study compared 2 herbal products to conventional dry cow therapy and no treatment for a total of 5 treatments over 2 trials. Trial 1 was conducted over 3 yr on 1 research farm and trial 2 included 4 commercial farms plus the research herd over 2 yr. Treatments included (1) a conventional IMM antibiotic and internal teat sealant (penicillin-dihydrostreptomycin and bismuth subnitrate; CON); (2) an herbal IMM product purported to act as a teat sealant (Cinnatube, New AgriTech Enterprises, Locke, NY; CIN); (3) an herbal IMM product (Phyto-Mast, Bovinity Health LLC, Narvon, PA; P-M); (4) Phyto-Mast and Cinnatube (PC); or (5) no dry cow therapy (NT). Each treatment group was balanced by breed, lactation number, due date, herd, and year. However, the CON treatment was used only in the research herd because of the intent to avoid antibiotic usage on the other 4 farms. Comparisons among treatments included the difference between pre- and posttreatment 305-d mature equivalent milk production (trial 1), somatic cell score change from dry-off to freshening at the cow and quarter levels (trials 1 and 2), and milk microbiology change over the dry period (trial 2). We detected no significant differences among treatments for milk yield differences between the lactation following treatment and the lactation preceding treatment. Changes in somatic cell score from one lactation to the next also did not differ significantly among treatments in either trial. Cure rates were not significantly different among treatments; only 19.6% of all quarters were infected at dry off. The proportion of quarters with new infections at 3 to 5d postcalving did not significantly differ among treatments, except between CIN and NT. Percentages (least squares means ± standard error) of quarters with new infections were 24 ± 21% for CON, 15 ± 7% for CIN, 30 ± 10% for P-M, 32 ± 11% for PC, and 35 ± 11% for NT. The efficacy of the herbal products was similar to that of conventional therapy, and the herbal products had no apparent adverse effects.

Keywords: alternative to antibiotics; dry cow therapy; organic mastitis treatment.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Anti-Bacterial Agents / therapeutic use
  • Bacterial Infections / drug therapy
  • Bacterial Infections / veterinary*
  • Bismuth / therapeutic use
  • Cattle
  • Diet / veterinary
  • Dihydrostreptomycin Sulfate / therapeutic use
  • Drugs, Chinese Herbal / administration & dosage*
  • Female
  • Food Contamination / prevention & control
  • Food Microbiology
  • Food, Organic / microbiology
  • Lactation
  • Mammary Glands, Animal / drug effects*
  • Mammary Glands, Animal / microbiology*
  • Mastitis, Bovine / drug therapy*
  • Mastitis, Bovine / microbiology
  • Milk* / microbiology
  • Penicillins / therapeutic use


  • Anti-Bacterial Agents
  • Drugs, Chinese Herbal
  • Penicillins
  • bismuth subnitrate
  • Dihydrostreptomycin Sulfate
  • Bismuth