Patterns of sedentary time and cardiometabolic risk among Canadian adults

Prev Med. 2014 Aug;65:23-7. doi: 10.1016/j.ypmed.2014.04.005. Epub 2014 Apr 13.

Abstract

Objective: The aim of this study is to examine the associations of total sedentary time and patterns of sedentary time with cardiometabolic biomarkers in a large representative sample of Canadian adults.

Methods: The study is based on 4935 adults aged 20-79years, from the 2007/09 and 2009/11 Canadian Health Measures Survey. Total sedentary time, patterns of sedentary time (≥20minute prolonged sedentary bouts, number of sedentary breaks), and moderate- to vigorous-intensity physical activity (MVPA) were accelerometer-derived. Waist circumference, systolic and diastolic blood pressure, high-density lipoprotein (HDL) cholesterol, and C-reactive protein were measured. Triglycerides, low-density lipoprotein (LDL) cholesterol, insulin, and glucose were also measured in a fasting sub-sample (n=2551).

Results: Total sedentary time and time in ≥20minute prolonged sedentary bouts were associated with higher insulin and lower diastolic blood pressure levels (P<0.05). On average, each additional 10 breaks/day was associated with 0.83 (95%CI: 1.35, 0.31) cm lower waist circumference, 0.32 (0.62, 0.02) mmHg lower systolic blood pressure, 0.01 (0.00, 0.02) mmol/l higher HDL-cholesterol, 3.72 (1.34, 6.13) % lower triglycerides, 0.57 (0.23, 0.92) % lower glucose, and 4.19 (1.80, 6.63) % lower insulin.

Conclusion: These findings in a large representative sample of Canadian adults indicate that breaking up sedentary time may be particularly important for cardiometabolic health.

Keywords: Adult; Cardiovascular diseases; Insulin resistance; Sedentary lifestyle.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Accelerometry
  • Adult
  • Aged
  • Biomarkers / blood
  • Canada / epidemiology
  • Cardiovascular Diseases / epidemiology*
  • Cardiovascular Diseases / etiology
  • Cardiovascular Diseases / prevention & control
  • Cross-Sectional Studies
  • Environmental Monitoring / instrumentation
  • Environmental Monitoring / methods
  • Female
  • Health Surveys
  • Humans
  • Insulin Resistance / physiology
  • Male
  • Metabolic Diseases / epidemiology*
  • Metabolic Diseases / etiology
  • Metabolic Diseases / prevention & control
  • Middle Aged
  • Motor Activity
  • Risk Assessment
  • Sedentary Behavior*
  • Time Factors
  • Young Adult

Substances

  • Biomarkers