The long-lasting effect of ferumoxytol on abdominal magnetic resonance imaging

J Comput Assist Tomogr. 2014 Jul-Aug;38(4):571-3. doi: 10.1097/RCT.0000000000000086.

Abstract

Ferumoxytol is a parenteral iron therapy that the Food and Drug Administration recently approved for the treatment of iron-deficiency anemia. The form of the iron, ultrasmall superparamagnetic iron oxide nanoparticles, causes T1, T2, and T2* shortening on magnetic resonance imaging, which can mimic hemosiderosis. We report such a case, with laboratory findings that demonstrate normal iron stores, and discuss the potential implications.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Glands / metabolism*
  • Adrenal Glands / pathology
  • Bone Marrow / metabolism*
  • Bone Marrow / pathology
  • False Positive Reactions
  • Female
  • Ferrosoferric Oxide / pharmacokinetics*
  • Hemosiderosis / diagnosis
  • Humans
  • Iron / blood
  • Liver / metabolism*
  • Liver / pathology
  • Liver Function Tests
  • Magnetic Resonance Imaging / methods*
  • Middle Aged
  • Parenteral Nutrition Solutions / metabolism
  • Spleen / metabolism*
  • Spleen / pathology

Substances

  • Parenteral Nutrition Solutions
  • Iron
  • Ferrosoferric Oxide