Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Apr;30(2):331-45.
doi: 10.1007/s12264-013-1410-3. Epub 2014 Apr 15.

Lipid Metabolism in Alzheimer's Disease

Free PMC article

Lipid Metabolism in Alzheimer's Disease

Qiang Liu et al. Neurosci Bull. .
Free PMC article


Lipids play crucial roles in cell signaling and various physiological processes, especially in the brain. Impaired lipid metabolism in the brain has been implicated in neurodegenerative diseases, such as Alzheimer's disease (AD), and other central nervous system insults. The brain contains thousands of lipid species, but the complex lipid compositional diversity and the function of each of lipid species are currently poorly understood. This review integrates current knowledge about major lipid changes with the molecular mechanisms that underlie AD pathogenesis.

Similar articles

See all similar articles

Cited by 16 articles

See all "Cited by" articles

Publication types