Normal and indeterminate pattern of fetal cardiotocography in admission test and pregnancy outcome

J Obstet Gynaecol Res. 2014 Mar;40(3):694-9. doi: 10.1111/jog.12226.

Abstract

Aim: The aim of this study was to evaluate the prognostic value of normal and indeterminate patterns of cardiotocography in admission test (AT) and pregnancy outcome.

Material and methods: A prospective study enrolled 818 intrapartum singleton pregnancies with gestational age of >34 weeks, in the latent phase and with intact membrane. Cases were divided into the high- and low-risk groups. Non-Stress Test was interpreted according to the 2008 National Institute of Child Health and Human Development workshop. Adverse pregnancy outcomes were compared between groups based on AT interpretation.

Results: Out of 818 patients, 492 (60%) were categorized as low-risk and 326 (40%) as high-risk pregnancies. In low-risk patients, 410 (83.3%) had normal and 82 (16.7%) had indeterminate AT. These figures were 249 (76.4%) and 77 (23.6%) in high-risk patients, respectively, and two cases (0.6%) had abnormal AT. In both groups, thick meconium staining, non-reassuring fetal heart rate pattern, cesarean section and cesarean section due to non-reassuring fetal heart rate pattern were significantly more frequent in indeterminate AT than normal ones (P < 0.001). In high-risk pregnancies with indeterminate AT, the risk of low birthweight and neonatal intensive care unit (NICU) admission increased. The positive predictive value was less than 30% in predicting thick meconium staining, non-reassuring fetal heart rate pattern, PH ≤ 7.2 and NICU admission in both groups. Overall, negative predictive value of AT for neonatal death and NICU admission was 100% and 96%, respectively.

Conclusions: Indeterminate patterns of cardiotocography can predict adverse pregnancy outcomes and when facing this condition, obstetricians should act cautiously.

Publication types

  • Validation Study

MeSH terms

  • Adult
  • Apgar Score
  • Cardiotocography*
  • Cesarean Section
  • Female
  • Fetal Distress / diagnosis*
  • Fetal Distress / epidemiology
  • Heart Rate, Fetal*
  • Hospitals, University
  • Humans
  • Incidence
  • Infant, Newborn
  • Intensive Care Units, Neonatal
  • Iran / epidemiology
  • Male
  • Meconium Aspiration Syndrome / diagnosis*
  • Meconium Aspiration Syndrome / epidemiology
  • Patient Admission
  • Pregnancy
  • Pregnancy Outcome
  • Pregnancy, High-Risk*
  • Prospective Studies
  • Risk Factors
  • Sensitivity and Specificity
  • Young Adult